Malaysian Journal of Chemistry, 2017, Vol. 19(1), 13–23
FeCl3/ AgOTf Catalyzed Hydroarylation Reactions of Aryl-substituted
Alkynes with Different Electron-rich Arenes
Md. Ataur Rahman1* and Tsugio Kitamura2
1Department of Chemistry, Jahangirnagar University, Savar, Dhaka-1342, Bangladesh.
2Department of Chemistry and Applied Chemistry, Graduate School of Science and Engineering, Saga University, Honjo-machi, Saga, 840-8502, Japan.
Received: June 2016; Accepted: January 2017
There are many synthetic methods for the direct formation of carbon-carbon bond between arenes and alkynes. Metal-catalyzed hydroarylation reaction is one of the synthetic methods for the direct formation of new carbon-carbon bond between arenes and alkynes. The hydroarylation reaction of aryl-substituted alkynes with arenes proceeded smoothly in the presence of FeCl3/AgOTf catalyst system in a mixed solvent of trifluoroacetic acid and dichloromethane at 30ºC and yielded aryl-substituted alkenes in moderate to high yields. Electron rich arenes gave high yields whereas the relatively less electron rich arenes gave norminal yields.
Key words: FeCl3/AgOTf catalyst; hydroarylation; alkynes; arenes; arylalkenes
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